Abstract

Comparative effectiveness research (CER), which refers to an evaluation of the clinical effectiveness of two or more medical interventions that are used to treat the same condition, has the potential to inform decision-making in both policy circles and physicians’ exam rooms. The ability of stakeholders to translate that research into practice has important implications for health outcomes, but the impact of information sources on physicians in translating CER remains understudied. This project examines the source-related influences on and motivations of cardiologists with respect to willingness to make changes in their practice based on emerging CER results. The results from this survey of cardiologists (N = 42) indicate that the source of information (including perceived credibility of those sources) matters greatly to cardiologists when deciding whether to make a change in practice. These findings suggest data-based implications for researchers and practitioners that are engaged in closing the CER translation gap.

Highlights

  • The term “Translational Research” first appeared in PubMed in 1993, and since scholars have increasingly taken on defining and studying the concept (De Maria Marchiano et al, 2021; DeMaria, 2013; Fort et al, 2017)

  • Comparative effectiveness research (CER), which refers to an evaluation of the clinical effectiveness of two or more medical interventions that are used to treat the same condition, has the potential to inform decision-making in both policy circles and physicians’ exam rooms

  • These findings suggest data-based implications for researchers and practitioners that are engaged in closing the CER translation gap

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Summary

Introduction

The term “Translational Research” first appeared in PubMed in 1993, and since scholars have increasingly taken on defining and studying the concept (De Maria Marchiano et al, 2021; DeMaria, 2013; Fort et al, 2017). The Institute of Medicine has advocated for the inclusion and meaningful participation of stakeholder involvement in many aspects of CER, including setting priorities and disseminating results (Devine et al, 2013; Sox & Greenfield, 2009) This is echoed by scholars who recognize that stakeholders in health care are likely to play different roles (fueled by different motivations) in the process of translating evidence-based research (e.g., translational research has its origins in the pharmaceutical industry) (Garland et al, 2021; Lean et al, 2008; Schumock & Pickard, 2018). In order to explore the role of information sources on physicians’ translation of CER, the following two research questions were developed: RQ1: Do sources of information, given a hypothetical scenario, differentially predict patterns of change in physician practice? RQ2: What characteristic(s) of information sources might motivate a behavioral response to that source? Given the exploratory nature of this topic, the present study concentrates on one case prompt and one physician specialty, both of which are described below

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