Abstract
Parabens are esters of p-hydroxybenzoic acid that are widely used in cosmetic, pharmaceutical, and industrial products, among other excipients, for their preservative and antimicrobial properties. However, since the late 1900s, parabens’ use and safety have been surrounded by controversies relating to the potential causes of endocrine disruption, infertility, allergic skin reactions, and various cancers. Despite parabens being under a cloud of suspicion, these compounds have succeeded in extensive skin testing conducted by a variety of organizations in the United States. By dispelling misconceptions about the Paraben Paradox Theory, our review is aimed at determining the safety of topically applied parabens in cosmetics, the availability of alternatives, and their side effects.
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