Abstract
Genetics has played a significant role in the interaction between the tobacco use and its environment which is evident through molecular epidemiological studies. This has come a long way in understanding the neurobiology of nicotine addiction, genetic polymorphism in demographic variables and treatment intervention. Molecular genetic studies in tobacco have further enhanced our understanding in modifying tobacco cessation therapy effectively in clinical setup. This has led to the concept of modifying the risk factors in public health. Understanding these interactions have led to the emphasis of tailor-made cessation therapy. Public health experts can overcome their weaknesses and threat in tobacco session through their strength and opportunities of scientific understanding of genetic and genetic polymorphism in tobacco cessation. It is important to understand that the given determinants just help in characterizing the risk and modifying risk factors still remains the best priorities in public health.
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