Abstract

Targeted post-exposure prophylaxis represents a more efficient use of the stockpile than treatment alone.

Highlights

  • The Australian health management plan for pandemic influenza (2008)[1] (AHMPPI) outlines a range of strategies aimed at eliminating an outbreak where possible, or reducing transmission sufficiently to allow distribution of a targeted vaccine

  • Modelling performed in the Australian context, where the number of stockpiled antiviral drug courses is 40% of the population size, has demonstrated that extensive drug distribution for preventive purposes does not compromise the ability to treat infected patients.[6]

  • One study considered four strategies for antiviral drug distribution when both drugs are available for treatment and prophylaxis.[8] It was concluded that a strategy whereby the smaller stockpile (drug B) is reserved for treatment, while the main stockpile (drug A) is used for prophylaxis, will most effectively delay the peak of the epidemic and result in the lowest overall level of drug resistance

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Summary

Introduction

Understanding Australia’s influenza pandemic policy on the strategic use of the antiviral drug stockpile: Targeted post-exposure prophylaxis represents a more efficient use of the stockpile than treatment alone

Results
Conclusion
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