Abstract
Foodborne pathogens such as Salmonella that survive cleaning and disinfection during poultry processing are a public health concern because pathogens that survive disinfectants have greater potential to exhibit resistance to antibiotics and disinfectants after their initial disinfectant challenge. While the mechanisms conferring antimicrobial resistance (AMR) after exposure to disinfectants is complex, understanding the effects of disinfectants on Salmonella in both their planktonic and biofilm states is becoming increasingly important, as AMR and disinfectant tolerant bacteria are becoming more prevalent in the food chain. This review examines the modes of action of various types of disinfectants commonly used during poultry processing (quaternary ammonium, organic acids, chlorine, alkaline detergents) and the mechanisms that may confer tolerance to disinfectants and cross-protection to antibiotics. The goal of this review article is to characterize the AMR profiles of Salmonella in both their planktonic and biofilm state that have been challenged with hexadecylpyridinium chloride (HDP), peracetic acid (PAA), sodium hypochlorite (SHY) and trisodium phosphate (TSP) in order to understand the risk of these disinfectants inducing AMR in surviving bacteria that may enter the food chain.
Highlights
Salmonella is a major foodborne pathogen worldwide and is highly associated with contaminated poultry products
The present review aims to understand how commonly used disinfectants such as hexadecylpyridinium chloride (HDP), peracetic acid (PAA), sodium hypochlorite (SHY) and trisodium phosphate (TSP) may confer antimicrobial resistance (AMR) in Salmonella in order to evaluate the risk of these disinfectants increasing AMR in surviving Salmonella
While more research is needed to further our understanding of AMR profiles from pathogens isolated from poultry processing facilities, this review suggests that understanding what AMR
Summary
Salmonella is a major foodborne pathogen worldwide and is highly associated with contaminated poultry products. All of thesemechanism characteristics appear quorum sensing—small signal molecules called autoinducers exchanged between bacteria as to be facilitated at least in part by an intercellular communication mechanism known as quoruma function of population density These signal moleculesexchanged can regulate expression of numerous genes, sensing—small signal molecules called autoinducers between bacteria as a function of including those associated with biofilm adherence, metabolism, and virulence. These signal molecules can regulate expression of numerous genes, including inhibitors of such factors may be key tometabolism, controlling biofilm formation pathogenicity [10,13,17–. Those associated with biofilm adherence, and virulence. Such factors may be key to controlling biofilm formation and pathogenicity [10,13,17,18,19]
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
