Abstract
Common side effects of antidepressants, such as weight gain, sexual dysfunction, and fatigue and sleepiness, may be attributable to their mechanisms of action. Antidepressants are neurotransmitter uptake blockers, enzyme inhibitors, and neurotransmitter receptor blockers. Various mechanisms of action can determine how quickly therapeutic benefit becomes apparent and whether certain acute and persistent side effects occur. Understanding mechanism of action can help clinicians select appropriate antidepressants for individual patients and manage adherence problems due to intolerability. Although more research is needed to further elucidate specific antidepressant mechanisms of action, clinicians can use current knowledge to tailor treatment decisions, such as switching patients to a medication with a different mechanism of action when intolerable adverse events are experienced.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
