Abstract
Introduction: Cardiovascular diseases are arguably the most important comorbidity in patients with chronic obstructive pulmonary disease (COPD). Despite an increased prevalence of coronary artery disease (CAD) in COPD patients, there are no dedicated diagnostic recommendations. Aims and Objective: The aim of the study was to investigate whether COPD patients receive adequate primary evaluation of CAD despite overlapping symptoms. Methods: 302 patients with COPD, who underwent invasive coronary angiography (ICA) were retrospectively matched (for age, BMI and cardiovascular risk factors) with 302 patients without functional lung diseases. Quality and onset of symptoms prior to ICA were documented and individual patients´ pretest probabilities according to ESC guidelines were calculated. Endpoints were delay of ICA referral after symptom onset and clinical outcome, defined as subsequent revascularization. Results: Mean delay between symptom onset and ICA was 19.9 ± 22.0 months in COPD patients compared to 8.3 ± 12.7 months in the control group (p Conclusion: Patients with COPD are insufficiently evaluated for CAD due to overlapping symptoms. Current CAD risk scores are inappropriate for patients with GOLD 2 or higher.
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