Abstract
Granular cell tumors are uncommon soft-tissue neoplasms of confirmed neural origin and are typically found in females of African descent between 30 and 60 years old.1-3 Most cases are found in the head and neck region, specifically the tongue, although there have been reports of other anatomic variants in patients outside of the typical epidemiology. We report a case of a granular cell tumor in a 10-year-old Caucasian female located on the left ventral upper arm with a biopsy confirming the histopathological diagnosis.
Highlights
Granular cell tumor is a term used to describe a group of soft tissue neoplasms with cells that are made of granular cytoplasm from the accumulation of lysosomal granules.[1]
Granular cell tumors are rare tumors that mostly occur in adults between 30 and 60 years old, with a 1:3 male-to-female ratio, and most often in individuals of African descent.[1,4]
Most cases present as a poorly defined solitary tumor and a large majority are typically found in the head and neck regions, with 30% located on the tongue because they develop from the gastrointestinal mucosa.[3,5]
Summary
Granular cell tumor is a term used to describe a group of soft tissue neoplasms with cells that are made of granular cytoplasm from the accumulation of lysosomal granules.[1]. We report a case of a granular cell tumor in a 10-yearold Caucasian female. A 10 year old Caucasian girl without prior medical conditions presented with a solitary bump on the left upper extremity present for an unknown amount of years. They denied pain, discharge from the area, or changes in growth of the lesion over time. One to three percent of cases are found to be malignant and are more likely to occur when the original tumor is found in viscera or deep soft tissue.[4]
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