Abstract
Abstract: For the first time, one-pot multicomponent reactions containing indole, aromatic aldehydes, and dimedone have been achieved in the absence of a catalyst under solvent-free conditions. A class of unsymmetrical indole-substituted methane derivatives and symmetrical diindolylmethanes has been synthesized through this green organic synthetic method. Based on experimental results, a reasonable mechanism for this condensation is emphasized here.
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