Abstract
All antiepileptic drug blood level determinations at the University of Virginia Medical Center were analyzed over a 13 month period.
Highlights
Of 28 cases of intracranial arachnoidal cysts reported from the Clinica Las Condes, Santiago, Chile, 17 were located in the middle cranial fossa, 3 in the quadrigeminal cistern, 2 were parasagital, 3 suprasellar and 3 were in the posterior fossa
The diagnosis of intracranial arachnoidal cysts and reports in the literature have become more frequent since the routine use of neuroimaging
For valproate (VPA), 15% of unbound values from 18% of patients were clinically significant with regard to current seizures and side effects and the rate was similar for monotherapy and polytherapy
Summary
Of 28 cases of intracranial arachnoidal cysts reported from the Clinica Las Condes, Santiago, Chile, 17 were located in the middle cranial fossa, 3 in the quadrigeminal cistern, 2 were parasagital, 3 suprasellar and 3 were in the posterior fossa. UNBOUND PIIENYTOIN AND VALPROATE MONITORING All antiepileptic drug blood level determinations at the University of Virginia Medical Center were analyzed over a 13 month period. Those values with unbound fractions outside the expected range and discordance between unbound and total levels were compared to seizure control and occurrence of side effects.
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