UMBILICAL CORD BLOOD ACID-BASE STATUS IN NEWBORNS WITH CONGENITAL HEART DISEASE IN A CARDIOVASCULAR REFERRAL CENTER IN COLOMBIA

Abstract

Introduction: Congenital heart diseases (CHD) represent the most frequent group of congenital disorders, with an incidence of 8 to 10 per 1000 live births. The aim of this study was assess the correlation between the presence of CHD and the acid base status of the umbilical cord blood at the Fundación Cardiovascular de Colombia during the period 2007-2018. Materials And Methods: Retrospective descriptive study in FCV, prior to authorization of the ethics committee, medical records were reviewed and with ICD10 codes the patients with CHD were identied everyone with prenatal echocardiography, CHD incompatible with life or incomplete records were excluded, It took a sample of arterial blood from the umbilical cord, the sample was processed in a gases machine (i-STAT300F), the data was collected in Excel, the heart diseases were classied according to the cardiopathophysiological classication, the association measure was -X2 Results: we met 111 patients with CHD, 56.7% men, in total 367 specic defects, grouped into 4 groups (IPB, DBPF, OBNSD and NSBC) with 157, 50, 77 and 58 respectively. The pH, HCO3, Pco2, Po2 in general without alterations. However, when we compare DPBF, it had an increase in the incidence of acidosis and mortality statistically signicant p = 0.005. Conclusions: according to the ndings, we can afrm that there are specic heart diseases such as DPBF, which predispose worse results, including acidosis and perinatal asphyxia. It also means that the changes in acid-base state in patients with CHD are not simply physiological variations, but are indicators of pathology and mortality, just as in patients without CHD.