Abstract

目的 研究新生儿脐血血气和乳酸对新生儿生后24 h内早期结局的预测作用。 方法 对2016年4月至2017年4月在北京新世纪妇儿医院产科出生的1 375例胎龄35周(及以上)无明显先天畸形的单胎活产新生儿进行前瞻性研究,生后1 min内进行脐血血气和乳酸检测,并观察新生儿生后24 h内的早期结局指标:是否复苏,1 min、5 min Apgar评分,是否入住新生儿病房,有无严重不良结局(插管、机械通气,新生儿窒息、缺氧缺血性脑病、胎粪吸入综合征,死亡)。 结果 胎龄35~41周(平均39周),脐血血气多元回归分析显示乳酸与pH、BE呈负相关(P 0.05)。 结论 单独乳酸水平的监测可以作为简易的脐血血气指标予以应用。新生儿脐血pH、BE和乳酸水平均可以预测新生儿是否需要复苏,但不能预测早期严重不良结局。

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