Abstract

In a previous paper it was reported that three hybrid cell lines between mouse lymphoma cells (L5178YS) and mouse fibroblasts (A9) were more resistant to x rays than either of the parental cells. In this work, these hybrids displayed a degree of resistance to uv light either higher than (hybrid clone 3) or similar to (hybrid clones 1 and 2) that of the more resistant parent (A9). The enhanced resistance of hybrid clone 3 to uv was related neither to changes in cell shape, ploidy, and growth rate nor to an increase in a caffeine-sensitive recovery process after uv irradiation.

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