Abstract
Male mouse submaxillary glands have been studied by electron microscopy at 1, 2, and 3 months following castration. The secretory tubules were reduced in volume and secretory granules reduced in number. The intracellular canaliculi became enlarged in the apical cytoplasm, and some appeared to be greatly distended. The dark cell of Pflüger could not be identified. Tubules similar to striated secretory tubules characteristics of the female gland occasionally were found. Castration does not result in the male gland becoming female in type—rather the gland of a male castrate is characteristic in appearance.
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