Abstract
Several types of neurosecretory fibers were observed in the normal infundibulum of the frog. After transection of the median eminence, these neurosecretory fibers of the proximal stump reacted asynchronously, but followed approximately the same pattern: a “passive accumulation” of granules observed early after the transection was followed by an “active axonal reaction” with the appearance of numerous tubular formations which are thought to be related to the Golgi apparatus. They filled the axon almost completely, and then became dilated and filled with an electron dense material. Subsequently these dilatations pinched off and gave origin to new neurosecretory granules. These locally packed granules plus others which were probably formed in more proximal parts of the axon, and the perikaryon and then transported distally, accumulated in the proximal axonal stumps and started to fill the fibers retrogradely.
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Schedule a callMore From: Zeitschrift fur Zellforschung und mikroskopische Anatomie (Vienna, Austria : 1948)
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