Abstract
Single and repeated hypoxic exposures induced different ultrastructural changes of varying intensity in adrenocorticocytes of rat adrenal zona fasciculata and zona reticularis. Destructive changes in cells were caused by the antianabolic effect of hypoxia and inhibition of regeneration and plastic processes. Treatment with nandrolone (Nerobolil, Gedeon Richter) diminished this effect and stimulated secretory activity of adrenocorticocytes.
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