Abstract
After 8 weeks of administration of gossypol (30 mg/kg/day for 6 days/week) to Wistar rats, the following changes in gonadotropic hormon (GTH) cells were observed by electron microscopic examination: slight to medium enlargement of rough endoplasmic reticulum and more apparent development of Golgi complexes in the cytoplasm. These findings suggested an enhanced secretory function. Moreover, increase of ring-shaped mitochondria, increase of lipid droplets and lysosomes, enlargement of smooth endoplasmic reticula and appearance of intracytoplasmic gaps in Sertoli cells were noted. However, no significant changes could be seen in Leydig cells.
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Schedule a callMore From: Journal of Tongji Medical University = Tong ji yi ke da xue xue bao
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