Abstract
Ultrastructural investigation of early replication in Drosophila polytene chromosomes
Highlights
Polyploidy reprograms regulatory pathways towards unicellular mode: the role in stress response, drug resistance, growth and cancer
Drosophila polytene chromosomes (PCh) are widely used as a model to delineate the functional organization of interphase chromosomes
That in general the spatio-temporal organization of replication in Drosophila chromosomes is closely related to the division of the genome into two types of domains, the rb-bands and the intervals in between them (INTs, corresponding to alternating zones of loose bands and interbands) (Kolesnikova et al, 2018)
Summary
Polyploidy reprograms regulatory pathways towards unicellular mode: the role in stress response, drug resistance, growth and cancer. Ultrastructural investigation of early replication in Drosophila polytene chromosomes Drosophila polytene chromosomes (PCh) are widely used as a model to delineate the functional organization of interphase chromosomes.
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