Abstract
Ultrastructural studies upon the development of coxsackievirus B-3 lesion in the olfactory bulb of the hibernating, experimentally infected adult squirrel (Citellus lateralis) revealed two or possibly three types of pathological reactions. (1) Changes, which occurred before virus replication in the brain, resembled an acute allergic reaction with extensive hemorrhages and neutrophil infiltration, fibrinoid deposits, thrombus formation, and lytic tissue breakdown in the neuropil. (2) Pathological changes resulting primarily from virus replication which succeeded the allergic reaction. (3) A reaction which coincided with and followed the virus replication and was associated with an influx of antibody-producing cells into the olfactory bulb and might prove to be the result of a delayed hypersensitivity.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
