Abstract
This study is undertaken in order to explore interaction between calcium phosphate bioceramics and surrounding tissues in the mandible of rabbit. The tissue response was evaluated 6 months after implantation of ceramics. Three kinds of porous bioceramics were studied: hydroxyapatite (HAp) and HAp mixture with β-tricalcium phosphate (95%HAp/5%β-TCP and 80%HAp/20%β-TCP). X-ray diffractometry (XRD), Fourier transform infrared spectroscopy (FT-IR) and scanning electron microscopy (SEM) were used to characterize porous bioceramic samples. Transmission electron microscopy (TEM), light microscopy and SEM examinations were applied for evaluation of interaction between tissues and bioceramics. The open porosity of obtained samples is in range between 50 to 60%. Pores have not specific form and mainly they are interconnected. The histological studies demonstrated appearance of a thick fibrous collagenous capsule formed around the pure HAp and presented by densely packed fibers and flattened fibrocytes, while addition of b-TCP evidenced highly vascularized adipose tissue.Keywords β-tricalcium phosphatehydroxyapatiteceramicstissueporous structurecellmicrostructure
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
