Year-end Sale % OFF 
Abstract
A convenient and efficient one-pot synthesis of 2-thioxo-dihydropyrimidine derivatives bearing piperidinylamide moiety is described. The reactions were carried out in 81-91% yields via the condensation of 1-(piperidin-1- yl)butane-1,3-dione with aromatic aldehyde and thiourea in ethanol catalyzed by p-toluenesulfonic acid at room temperature under ultrasound irradiation. The advantages of this methodology are convenient operation, mild conditions, short reaction times and high yields. Keywords: Catalysis, condensation, one-pot synthesis, piperidinylamide, 2-thioxo-dihydropyrimidine, ultrasound irradiation.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
