Abstract
In the development of novel antimicrobial agents, we synthesized novel 1,2,3‐triazole‐based pyrazole and pyrimidine derivatives 6(a–f) and 7(a–f) by ultrasound‐assisted method. The synthesized compounds were characterized by IR, 1H NMR, 13C NMR, MS, and elemental analysis. All compounds were assessed in vitro for their efficacy as antimicrobial agents against four bacteria (Staphylococcus aureus, Bacillus subtilis, Escherichia coli, and Pseudomonas aeruginosa) and two fungi (Candida albicans and Aspergillus niger). In particular, compounds 6a, 6e, 7a, 7c, and 7e exhibited highly potent antimicrobial activity.
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