Abstract
Purpose: To evaluate the usefulness of ultrasound guidance in percutaneous needle biopsy for musculoskeletal tumours. Methods: Forty-five consecutive patients underwent ultrasound-guided needle biopsy. An additional group of 50 patients who underwent needle biopsy without ultrasound guidance was retrospectively selected as historical control. The sample was considered adequate when a diagnosis can be made, and diagnostic when the diagnosis is similar to the final report based on the excised tumour. Results: Adequacy of the biopsy samples was 84% in ultrasound-guided group as compared 76% in the group with no ultrasound guidance. Diagnostic accuracy was 64% in the ultrasound-guided group and 52% in the group without ultrasound guidance. Both of these differences were not statistically significant. Conclusions: Ultrasound guidance did not provide a significant advantage in the biopsy of musculoskeletal tumours. Diagnostic accuracy seems to improve with the use of larger 14 gauge biopsy needle but further evaluation is necessary.
Highlights
Musculoskeletal tumour is relatively uncommon and an accurate ratio of benign to malignant lesions is difficult to determine
We conducted this study to determine the efficacy of ultrasound-guided needle biopsy for musculoskeletal tumour
Fifty consecutive cases of musculoskeletal tumours, at the same institution between 1998 and 2000 were selected as historical controls
Summary
Musculoskeletal tumour is relatively uncommon and an accurate ratio of benign to malignant lesions is difficult to determine. Definitive diagnosis of the tumour is generally dependent on histopathological interpretation. Open biopsy remains the gold standard because it provides more tissue sample for examination compared to the less invasive needle biopsy. Some clinicians attempt to improve the diagnostic outcome of needle biopsy with the use of imaging techniques like image intensifiers or computerized tomography (CT scan). High-resolution real time ultrasound allows for visualization of tissues of varying echogenicity and may provide guidance for the placement of biopsy needle. We conducted this study to determine the efficacy of ultrasound-guided needle biopsy for musculoskeletal tumour
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