Abstract
Highlights •In a porcine model, we investigated the therapeutic effectiveness of microbubble enhanced sonothrombolysis for treatment of catheter-induced vasospasm and vascular injury, a common complication after femoral arterial catheterization, particularly in children. •Our results show that microbubble cavitation mediated by brief application of diagnostic high mechanical index impulses is an effective noninvasive method for relieving catheter-induced vasospasm. •This approach could have potential as an effective treatment for reversal of pulse loss after peripheral arterial injury and vasospasm.
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