Abstract
Thermal therapies for cancer treatment have achieved a high level of interest in the medical society, especially for treatment of liver metastases. Laser-induced thermo therapy (LITT) is one of the most promising techniques for minimally invasive destruction of tumors through coagulation. The precision and efficiency of this treatment could be markedly improved by noninvasive monitoring of either temperature distribution in the tissue or by direct demarcation of the destructed zone. The purpose of this report is to demonstrate that parametric ultrasound imaging provides an efficient method for localizing the coagulated area during the treatment. An on-line time-of-flight velocimetry for temperature mapping as well as a mapping of the structural changes through measurement of changes in the attenuation coefficient are presented. The coagulation of porcine liver in vitro and in vivo has been performed by Nd:YAG laser radiation while access to the radio-frequency signals of a conventional ultrasound system served for collection of acoustical parameters from the treated zone. The introduced system is capable of acquiring 12 B-scans/sec with a mean spatial resolution of 1 mm. Quantitative parameters for the control of LITT treatments are derived.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
