Abstract

BackgroundOne of the challenges that anesthesiologist faces is the intra- and postoperative analgesia in cases of cleft lip repair in pediatrics. However, the use of ultrasound infraorbital nerve (ION) block has not been evaluated before in pediatric. This prospective randomized double-blinded study was designed to evaluate the analgesic efficacy of ultrasound-guided ION block in infants undergoing unilateral cleft lip repair.MethodsSixty infants (ASA status I, II) aged 3–10 months undergoing unilateral cleft lip repair were allocated randomly to two groups (n = 30 each). The bupivacaine group (group B) received ION block with 1 ml 0.25% bupivacaine, and the saline group (group S) received 0.9% normal saline 1 ml in each side by the use of ultrasound. Intraoperative measurements included heart rate and mean arterial blood pressure. Postoperative pain score was recorded at 15 and 30 min, then at 2, 6, 10, and 16 h. If the score exceeded 3 points, 25 mg/kg of paracetamol suppository was given, with recording the time of first rescue analgesia and total dose given in each group.ResultsPostoperative pain, using FLACC (Face, Legs, Activity, Cry, Consolability) score the median scores were higher in the saline group than bupivacaine group at 15 min, 30 min, 2 h, 6 h and 10 h. There was significantly longer time in the bupivacaine group than the saline group for first rescue analgesia (476.6 ± 100.7 vs 21 ± 6 min respectively, P ˂ 0.001). Whereas more number of paracetamol doses were required in the saline group when compared to bupivacaine group, total dose of paracetamol was significantly lower in the B group than the S group.ConclusionsUltrasound-guided bilateral ION block provides a superior postoperative analgesia for infants undergoing cleft lip repair. It is a simple and easy to perform technique, with high success rate and minimal complications.

Highlights

  • One of the challenges that anesthesiologist faces is the intra- and postoperative analgesia in cases of cleft lip repair in pediatrics

  • The aim of the present study is to evaluate the use of ultrasound-guided infraorbital nerve (ION) block in cleft lip repair as a tool of intra- and postoperative analgesia with recording of its possible side effects

  • After ethical committee approval and written informed consent from the parents, 60 infants were undergoing a repair of unilateral cleft lip, with an age between 3 and 10 months of both sexes, with American Society of Anesthesiologists (ASA) I–II, and weighing between 5 and 12 kg were included in the study

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Summary

Introduction

One of the challenges that anesthesiologist faces is the intra- and postoperative analgesia in cases of cleft lip repair in pediatrics. The use of ultrasound infraorbital nerve (ION) block has not been evaluated before in pediatric. This prospective randomized double-blinded study was designed to evaluate the analgesic efficacy of ultrasound-guided ION block in infants undergoing unilateral cleft lip repair. The aim of the present study is to evaluate the use of ultrasound-guided ION block in cleft lip repair as a tool of intra- and postoperative analgesia (primary outcome) with recording of its possible side effects

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