Ultrasound features changing during uveal melanoma local treatment

Abstract

AbstractPurpose The aim of our study was to estimate the echographic sighs (acouctic densitometry characteristics and hemodynamic changes in tumoral vascular network) of uveal melanoma during the local irradiation.Methods 58 patients (31‐74 years old) with uveal melanoma underwent the investigation. Acoustic densitometry and hemodynamic characteristics in tumoral vessels were estimated both before and during brachytherapy using high‐resolution duplex scanning (using ultrasound system Voluson® 730Pro, GE Medical Systems, Kretz Ultrasound).Results There were estimated some alterations in echographic sighs which included the increasing of blood flow velocity in tumoral vessels and decreasing the acoustic densitometry characteristics during the local treatment in comparison with those before the treatment. The dimension and the degree of intensity those alterations depended on tumor size, it’s localization in the eye, facility of the irradiation, angioarchitecture of the lesion.Conclusion The estimation of echographic alterations in uveal melanoma during the local treatment allows indirectly to judge about tumor radiosensivity and probably to assume the local treatment efficiency.