Abstract

The objective. Іs to investigate the state of the mammary glands in patients with infertility of endocrine genesis. Materials and methods. The study was conducted in 110 patients with endocrine infertility who underwent an ultrasound examination of the mammary glands. The first group (n=52) consisted of patients with a regular menstrual cycle against the background of luteal phase insufficiency, the second group (n=58) consisted of patients with a menstrual cycle disorder with anovulation. Statistical processing of the research results was carried out using the standard programs "Microsoft Excel 5.0" and "Statistica 8.0". Results and their discussion. Changes in the mammary glands according to the type of PCH in the studied group were found in 44 out of 110 patients (40.0%), underdevelopment of the structural elements of the mammary glands - in 19 out of 110 (17.3%), early involutional changes - in 6 out of 110 (65, 4%), focal formations – in 4 out of 110 (3.6%). The frequency of fibrocystic disease in patients of the II group was 1.3 times higher compared to the I group - 24 (41.3%) versus 20 (38.4%), respectively, p<0.01. At the same time, focal mammary gland formations of the fibroadenoma type were diagnosed 3.5 times more often in patients of the I group - 3 (5.8%) versus 1 (1.7%) in the II group, p<0,01. Conclusions. In infertility of endocrine genesis, the first place in the structure of mammary gland pathology is diffuse fibrocystic disease - 40.0%. The frequency of underdevelopment of mammary glands is 17.3%, early involutional changes 10.3%, and focal formations like fibroadenoma are 3.6% of cases.

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