Abstract
THE PURPOSE OF THE STUD. Determination of ultrasound semiotics of Crohn’s disease and ulcerative colitis by evaluation of activity of inflammatory process, assessment of the possibilities of echography in the differential diagnosis of these diseases. MATERIALS AND METHODS. The study included 91 patients between the ages of 4 months up to 17 years. There were examined 24 patients with verified Crohn's disease and 37 patients with verified ulcerative colitis. 30 patients without any clinical and laboratory data of the gastrointestinal diseases were included in to control group. Bowel ultrasound was done without any preparation and contrast enhancement. RESULT OF RESEARCH. Sensitivity of the test «bowel wall thickness >2.5 mm - inflammatory bowel disease» - 90,2 %, specificity - 100.0 %, positive predictive value -100.0 %, negative predictive value - 83,3 %, and AUC - 0,957. Sensitivity of the test «doppler signals amount in bowel wall >2 - inflammatory bowel disease» - 93,4 %, specificity -100.0 %, positive predictive value - 100.0 %, negative predictive value - 88,2 %, and AUC -0,967. Significant differences in pathological vascularization, ascites, terminal ileum affection, mesentery and (or) omentum inflammatory infiltration and lymph nodes size were revealed between group ofCrohn's disease and ulcerative colitis (P<0,05 for all comparisons). Significant differences in pathological vascularization during the activity and remission periods were revealed in all groups; in lymphatic nodes size - in group of ulcerative colitis and combined group of bowel inflammatory disease; in ascites, terminal ileum affection, and mesentery and (or) omentum inflammatory infiltration - in group of Crohn's disease (P<0.05 for all comparisons). CONCLUSION. Ultrasound examination is an essential method in the diagnosis and monitoring of inflammatory bowel disease in children.
Highlights
ФГБУ ДПО «Российская медицинская академия непрерывного профессионального образования» Министерства здравоохранения Российской Федерации, кафедра лучевой диагностики детского возраста, г
При сравнении периодов обострения и ремиссии достоверные различия получены по патологической васкуляризации во всех группах; по размерам лимфатических узлов – в группе «язвенный колит» и объединенной группе воспалительных заболеваний кишечника; по наличию асцита, поражения терминального отдела кишечника и воспалитель ной инфильтрации брыжейки и сальника – в группе «болезнь Крона» (P
Sensitivity of the test «doppler signals amount in bowel wall >2 – inflammatory bowel disease» – 93,4 %, specificity – 100.0 %, positive predictive value – 100.0 %, negative predictive value – 88,2 %, and AUC –0,967
Summary
При сравнении периодов обострения и ремиссии достоверные различия получены по патологической васкуляризации во всех группах; по размерам лимфатических узлов – в группе «язвенный колит» и объединенной группе воспалительных заболеваний кишечника; по наличию асцита, поражения терминального отдела кишечника и воспалитель ной инфильтрации брыжейки и (или) сальника – в группе «болезнь Крона» (P
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