Ultrasound assisted synthesis of CoFe-LDH for the simultaneous electrochemical detection of dopamine and acetaminophen

Abstract

Herein, CoFe layered double hydroxide composites (CoFe-LDH) were synthesised by a simple ultrasound assisted synthesis method. It has been characterized by scanning electron microscopy (SEM), X-ray diffraction and X-ray photoelectron spectroscopy. CoFe-LDH modified glass carbon electrode was used as dual-function sensors for DA and AP detection. The sensor exhibits a wide detection linear range for DA and AP (2 μM-900 μM), low detection limits (DA: 0.08 μM; AP: 0.37 μM) (S/N = 3). The sensitivity of CoFe-LDH/GCE for DA and AP were 0.54 μA μM−1 cm−2 and 0.55 μA μM−1 cm−2. And it shows good reproducibility, selectivity, and stability. In addition, the sensor demonstrated good recovery rates for the detection of DA and AP in human serum samples.