Abstract
We report two cases of Cantrell's Pentalogy detected by ultrasonography at 24 and 25.5 weeks of gestation, respectively and confirmed at autopsy. Cantrell's Pentalogy consists of defects of the lower sternum, anterior diaphragm, midline supraumbilical abdominal wall and diaphragmatic pericardium with ectopia cordis. Our cases showed all these defects along with a bilateral cleft lip and cleft palate in the 24 week fetus. Association of cleft lip and cleft palate with Pentalogy of Cantrell may represent an extension of the basic defect in the migration of mesodermal primordial structures that involve the abdominal and thoracic midline fusion defects of the syndrome to also involve the facial structures, which must therefore be thoroughly looked for in all such cases.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
