Ultrasonographic and pathomorphological changes in Alimentary Lymphoma in cats

Abstract

The study aimed to determine the characteristic changes in alimentary lymphoma in cats during ultrasonography, pathoanatomic and cytological examination of biopsy material. The survey objects are cats with gastroenterological disorders with suspected alimentary lymphoma of different ages and genders. The diagnosis was made based on a clinical examination according to generally accepted methods, laboratory blood examination, ultrasound examination, pathomorphological examination of the intestinal walls and lymph nodes, and cytological examination of the lymph node material obtained by the TIAB method. The authors carried out the material sampling for cytological examination using percutaneous fine needle aspiration (FNA) biopsy under ultrasound control on the Mindray Z6 Vet apparatus. In addition, the authors conducted pathological and cytological studies in the Vet Union laboratory. When analyzing ultrasound examination in cats diagnosed with alimentary lymphoma, hepatomegaly, 1% ascites, 3% hydrothorax, 3 % increase in mediastinal lymph nodes, 7% splenomegaly, 16% violation of differentiation of intestinal layers, 16% violation of differentiation of intestinal layers, 29% increase in mesenteric lymph nodes, 29 % thickening of intestinal walls were observed in 12% of cases. Cytological examination revealed rounded, large, separately located cells. The population is monomorphic. During a histological study in the intestinal wall, adjacent fatty tissue of the omentum, and lymph node tissue, there is a highly cellular invasive formation constructed from diffuse layers of rounded lymphoid neoplastic cells with a scanty fibrous stroma. The most characteristic ultrasound findings are the thickening of the intestinal walls and an increase in mesenteric lymph nodes.