Abstract
In this lecture, a review is made of recent work and concepts dealing with the insonation of nucleic acids (DNA, RNA transfer, etc.). Possible implications in the field of genetics are reviewed briefly. The role of free radicals during the insonation of microorganisms is analyzed with particular emphasis on the behavior of highly resistant spore strains. A new sterilization theory is exposed which is based upon synergistic effects observed during the insonation of aqueous glutaraldehyde solutions at reasonably low temperature (54°C). Results obtained with resistant B. subtilis spores (including AOAC) are given. Conclusions are drawn regarding the use of this technique in hospitals and industry (continuous sterilization of disposables). Economic aspects of the new synergistic sterilization method are analyzed.
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