Abstract

Ultrasound technique represents a green method for the synthesis of different class of compounds. In this review, the progress in the synthesis of aminophosphonates, an important class of phosphorus derivatives having biological applications, under sonication, with or without catalysts or solvents, is presented. Aminophosphonates were obtained in very good yield from amines, aldehydes (ketones), and dialkyl or trialkyl phosphites under ultrasound. Ultrasound had a notable effect on the reaction conditions, the purity and yield of obtained compounds. Aminophosphonates which cannot be obtained by traditional methods were obtained when ultrasound is used.

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