Abstract
The ultrasonic absorption coefficient was examined in rat liver due to the effects of 1% dietary orotic acid measured using the transient thermoelectric technique @ 1MHz. Dietary orotic acid causes fat concentration to accumulate excessively in rats in a short period of time. Tissue constitutes that are particularly important in absorption are water, protein, collagen, and lipid levels. The concentration of these tissues constitutes in rat liver over a 0‐to 10‐day period on the orotic acid diet compared to the absorption coefficient suggest that ultrasonic properties can be modeled as a function of constitute concentrations. Using the statistical analysis system, comparisons were made between the tissue constitutes and ultrasonic absorption coefficient where comparisons are significant at the p < 0.05 level. Lipid levels of the fatty liver were shown to be statistically significant to the absorption coefficient. Strong correlations of both collagen and protein with absorption, which have p values of 0.098 and 0.071, respectively, were observed. [Work supported by NIH Grant CA36029.]
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