Abstract

We report a facile one step hydrothermal method to synthesize TiO2 nanoparticles decorated by reduced graphene oxide (rGO) sheets. The morphology and chemical composition of the prepared TiO2/rGO nanocomposite were examined by using suitable characterization techniques. The TiO2/rGO nanocomposite was used to modify the glassy carbon electrode (GCE), which showed an effective electrochemical sensing platform for the detection of RIF, when compared to bare GCE. The differential pulse voltammetric studies, as prepared TiO2/rGO nanocomposite exhibited an extraordinary performance in quantifying the RIF. The fabricated sensor showed a low electrochemical detection limit of 0.03 µM over the linear dynamic range 0.01- 1 µM. The proposed electrochemical sensor was successfully employed for the determination of RIF in pharmaceuticals and biological fluids with good recoveries.

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