Abstract

We propose an implantable CMOS micro system for detection of neural spike signals from complex brain neural potentials which achieves the characteristics of ultra low-power and high-precision. The neural recording micro system consists of a low-noise bioamplifier, a neural spike detector based on nonlinear energy operator (NEO) and a precision hysteresis comparator. The DC offset in the bioamplifier is rejected by introducing a new active feedback configuration instead of the large capacitors, the NEO algorithm is implemented through simple analog circuits operating in sub-threshold region, and the hysteresis comparator is added to determine the location of neural spike. The current consumption of the recording system is 3.02 μA with 3.3 V supply. The proposed system has been implemented in 0.35 μm CMOS process and precisely detects neural spike signals from extra cellular recording.

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