Abstract
We propose a novel technique for measuring directly in real time, locally and non-invasively the pulse wave velocity (PWV) on peripheral arteries. Very high frame rate ultrasonic imaging (> 1000 frames/s) was achieved for tracking in 2D the propagation of transient vibrations along arterial wall. The arterial pulse waves are observed within a single cardiac cycle allowing the estimation of the pulse wave velocity with a good accuracy. In this study, this technique was validated for PWV evaluation on 25 healthy patients using conventional sonographic probes. The mean carotid PWV was found to be 5.5 ± 1.2 m/s (from 4.5 m/s to 7 m/s) with good intra and interobserver variability (inferior of 10% of the mean). These data suggest a good accuracy and reproducibility of the technique for real time PWV evaluation in vitro and on healthy volunteers.
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