Abstract

Abstract Data accumulated in recent years have shown the existence of multiple about 90 min ultradian rhythms in gastric motility, urine flow and osmolality and physiologic indices of arousal. While these data support Kleitman's hypothesis that the REM‐NONREM sleep cycles are only fragments of a 24‐h rhythm (Basic Rest‐Activity Cycle) which is manifested in wakefulness in recurrent fluctuations in arousal, it further indicates that both the sleep and the waking rhythms are part of a more complex multioscillatory system with a dominant periodicity centered at 90 min.

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