Abstract

Ultrasmall superparamagnetic iron oxide nanoparticles (USPION) as magnetic resonance imaging were synthesized through a sonochemical co-precipitation method with poly (ethyleneimine) (PEI). The size of the USPION was controlled by poly (ethyleneimine) (PEI) contents, ultrasonic exposure time, and Na4OH concentration. The characteristics of PEI-USPION were studied by X-ray diffractometry, magnetic property measurement system, scanning electron microscopy, transmission electron microscopy, and particle size analysis. The PEI-USPION had an average size of 5~10nm with a narrow size distribution, a perfect magnetite crystal structure, and high saturation magnetization.

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