Abstract
Ultra-Highly Diluted Homeopathic Remedy Arnica Montana 30C can Reduce UV-induced DNA Damage in Escherichia coli through its Regulatory Influence on Nucleotide Excision Repair Genes: A Commentary on our Published Research Finding
Highlights
Ultra-violet (UV) radiation is an effective carcinogenic and mutagenic agent which is known to interact either directly with DNA or indirectly through generation of free radicals or reactive oxygen species (ROS), and can inflict DNA damage or alter the genomic integrity [1,2,3,4]
Arnica Montana 30C (AM-30C) upregulated the expression of the repair genes uvr A, B and C, validating prima facie the “gene regulatory hypothesis” that claims ultra-highly diluted homeopathic drugs to act through regulation of relevant gene expressions as the most plausible molecular mechanism
The biochemical and molecular repair pathways have been extensively investigated in some model organisms such as Escherichia coli, Saccharomyces cerevisiae, and human [7], where specialized repair mechanisms are put in place
Summary
Ultra-violet (UV) radiation is an effective carcinogenic and mutagenic agent which is known to interact either directly with DNA or indirectly through generation of free radicals or reactive oxygen species (ROS), and can inflict DNA damage or alter the genomic integrity [1,2,3,4]. This can drastically affect the normal life processes of all organisms ranging from lower prokaryotes to higher eukaryotes [5,6]. The repair mechanism involves certain proteins which are recruited to scan the genome continuously and detect DNA lesions, if any
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
