Abstract
DLNR was applied on whole-body images recorded after the injection of 545 ± 33MBq of [99mTc]Tc-HDP in 19 patients (14 with bone metastasis) and reconstructed with 100%, 90%, 80%, 70%, 60%, 50%, 40%, and 30% of the original SPECT recording times. Irrespective of recording time, DLNR enhanced the contrast-to-noise ratios and slightly decreased the standardized uptake values of bone lesions. Except in one markedly obese patient, the quality of DLNR processed images remained good-to-excellent down to 60% of the recording time, corresponding to around 6min SPECT-recording. Ultra-fast SPECT recordings of 6min can be achieved when DLNR is applied on whole-body bone 360° CZT-SPECT.
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