Abstract

We demonstrate an ultrafast displaying Spectral Domain Optical Doppler Tomography system using Graphics Processing Unit (GPU) computing. The calculation of FFT and the Doppler frequency shift is accelerated by the GPU. Our system can display processed OCT and ODT images simultaneously in real time at 120 fps for 1,024 pixels × 512 lateral A-scans. The computing time for the Doppler information was dependent on the size of the moving average window, but with a window size of 32 pixels the ODT computation time is only 8.3 ms, which is comparable to the data acquisition time. Also the phase noise decreases significantly with the window size. Since the performance of a real-time display for OCT/ODT is very important for clinical applications that need immediate diagnosis for screening or biopsy. Intraoperative surgery can take much benefit from the real-time display flow rate information from the technology. Moreover, the GPU is an attractive tool for clinical and commercial systems for functional OCT features as well.

Highlights

  • Optical Coherence Tomography (OCT) has been widely accepted as a non-invasive high resolution imaging modality for in vivo biological specimens [1]

  • Developed Graphics Processing Units (GPUs) enable very fast processing of OCT signals, and can execute parallel, general purpose numerical solutions surpassing the use of CPUs

  • We demonstrate an ultrafast displaying Spectral Domain Optical Doppler Tomography (SD-ODT) using GPU computing

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Summary

Introduction

Optical Coherence Tomography (OCT) has been widely accepted as a non-invasive high resolution imaging modality for in vivo biological specimens [1]. Developed Graphics Processing Units (GPUs) enable very fast processing of OCT signals, and can execute parallel, general purpose numerical solutions surpassing the use of CPUs. Several years ago NVIDIA Corporation presented a parallel computing architecture named Compute Unified Device Architecture (CUDA) commonly adapted in computer games for more natural presentation of sceneries. Use of GPUs in the OCT research field for fast display of intensity images has been reported several times [5,6,7,8]. We report a novel ultra-fast displaying Spectral Domain Optical Doppler Tomography (SD-ODT) by use of CUDA processes for real-time display of OCT intensity and Doppler images simultaneously at a frame rate of 120 fps for a 2,048 × 512 pixel image size

System Configuration and Signal Processing Architecture
Doppler Frequency Shift
ODT Data Processing
Results and ODT Imaging
Discussion and Conclusions
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