Abstract
Ultra-deep sequencing of HIV-1 near full-length and partial proviral genomes among chronically infected blood donors at four blood centers in Brazil
Highlights
We aimed to gain a comprehensive picture of HIV-1 diversity in the north-east and south-east part of Brazil
A high-throughput sequencing was used to characterize the near full length (NFLG) and partial HIV-1 proviral genome in blood donors at four major blood centers in Brazil: Pro-Sangue foundation (São Paulo state (SP), n 48), Hemominas foundation (Minas Gerais state (MG), n 41), Hemope foundation (Recife state (PE), n 97) and Hemorio blood bank (Rio de Janeiro (RJ), n 90)
Of the 294 samples studied, 229 (77.9%) NFLGs and 50 (17%) partial fragments were de novo assembled into contiguous sequences and successfully subtyped
Summary
Rodrigo Pessôa1*, Jaqueline Tomoko Watanabe, Paula Loureiro, Maria Esther Lopes, Anna Barbara Carneiro-Proietti, Ester C Sabin, Michael P Busc, Sabri S Sanabani. From International Symposium HIV and Emerging Infectious Diseases 2014 Marseille, France. 21-23 May 2013
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