Abstract

Ulcerative colitis (UC) is a chronic nonspecific inflammatory disease caused by immune disorders, mental disorders, genetics, and other factors. Its main clinical manifestations are accompanied by abdominal pain, diarrhea, bloody stools, weight loss, etc. A distinctive feature of nonspecific ulcerative colitis from Crohn's disease is its limitation by the large intestine, as well as the limited inflammation of the mucous membrane [1]. The disease affects various age groups from infants to the elderly, with a maximum incidence rate between the ages of 15 to 30 years and between 50 and 70 years. UC seriously affects human health and quality of life because of its long duration and repeated attacks, and also there is a risk of developing colorectal cancer. The disease violates the quality of life and leads to disability [2]. The article presents the causes of ulcerative colitis and describes the mechanisms for the development of pathological changes in the intestine. The principles of patient management, taking into account the severity of the disease, and the tactics of rational drug therapy are presented.

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