Abstract
Has been research about influence of ethanol extract of leaves of soursop ( Annona muricata L.) on the formation of coronary artery atherosclerosis of male quail induced high fat feeding and propylthiourasil. Male quail were divided into five groups , each group getting treatment. Negative controls given standard diet, a positive control was given high fat feeding and propylthiouracil, doses of 50, 100, 200 mg / kg BW ethanol extract administered orally soursop leaves. The treatment is done for 60 day, then take heart, be making preparations histopathology and staining haematoxyllin-eosin. The results showed that the ethanol extract of leaves of soursop dose 50 mg / kg BW selective in preventing atherosclerosis in male quail, when compared with the positive control ( P < 0.05 ). While the administration at a dose of 100 and 200 mg / kg showed no selective in preventing atherosclerosis in male quail, when compared with the positive control .
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