Тuberculous spondylitis in HIV-positive and HIV-negative patients: analysis of comorbidity and influence of premorbid background on the formation of infectious postoperative complications

Abstract

The aim of the study was to study comorbidity in HIV (+) and HIV (–) patients with tuberculosis spondylitis (TS) and to assess the influence of certain perioperative risk factors on the formation of early and late postoperative infectious complications.Materials and methods. A retrospective analysis of 274 patients with TS was performed: 116/43.2% of patients HIV (+) (group 1) and 158/57,7% HIV (–) (group 2). We studied the risk factors for postoperative complications: age, alimentary disorders, concomitant diseases, and the risk of surgical intervention on the ASA scale.Research result. TC patients in 88,3% of cases had comorbidities (ASA Class 3–4). Early and late infectious complications were 1,5–2 times more common in TC patients with ASA Class 4 than in ASA Class 3. In the HIV (+) group, early infectious complications prevailed, while in HIV (–) patients, these complications occurred with the same frequency. Late postoperative complications were 3–5 times more common in HIV (+) patients (OR=2,84 and OR=8,56, respectively).