Abstract

Male sheep immunized with crystallized 1,6-diphosphofructose aldolase produce nonprecipitating antibodies which inhibit the enzyme activity of the muscle aldolase in different organs and species. The presence of these antibodies is proven by the haemagglutination test. Anti-muscle aldolase does not affect the aldolase activity of the liver. Most of the aldolase activity present in normal human serum is derived from the muscle and is therefore inhibited by the presence of antibodies.

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