Uşak İlinde Çocuklarda Üriner Sistem Enfeksiyonlarının Mikrobiyolojik ve Antimikrobiyal Profili

Abstract

Aim: One of the most prevalent pediatric diseases is urinary tract infection (UTI), accounting for 3% of all infections among the pediatric population and affect 2% of males and 8% of females by age seven. Bacteria are the most prevalent cause of UTIs, accounting for more than 95 percent of cases. The most prevalent causal bacteria of UTI is Escherichia coli. Antibiotics are included in the treatment of these infections. As a result, determining the correct antibiotic susceptibility is critical in the therapeutic treatment of bacterial infections. This study aimed to analyse the aetiology and antimicrobial resistance characteristics of urinary tract infection among children presenting with symptoms in Uşak. Material and Method: A total of 1250 urine culture results were retrospectively analyzed from pediatric patients aged 0–16 years who were admitted to Uşak Öztan Hospital as outpatients with symptoms and complaints of urinary tract infection and whose urine analysis and urine culture were taken between January 2018 and December 2020. Result: Gram-negative microorganism growth was found in 238 (19%) of the 1250 pediatric patients evaluated in our study. There was no growth in the urine cultures of 877 (70%) patients. E. coli was the most isolated microorganism in our study, which was detected in 168 (70.5%) of the patients. Conclusions: We present the first antimicrobial resistance data for the city of Uşak. Our study showed that amoxicillin/clavulanate is not the best option for the empirical therapy of community acquired UTIs, contrary to current local practice. In addition, ceftriaxone was found to be the second most resistant antibiotic in our study.