Abstract
The activities of tyrosine hydroxylase (TH), tryptophan hydroxylase (TPH), and the concentrations of biopterin (BP) and neopterin (NP) were examined in postmortem brains from histologically verified patients of senile dementia of Alzheimer type (SDAT). The results suggest that the reductions in TH, TPH, and BP may be related to the reduction in monoamine neurotransmitters, due to destruction of monoaminergic neurons in SDAT, and may be an event independent of the cholinergic dysfunction. Serum BP levels were also significantly reduced in patients with SDAT.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
